Covid 19 Booster Shots for Moderately or Severely Immunocompromised People
People with moderately to severely compromised immune systems are especially vulnerable to COVID-
19, and may not build the same level of immunity to 2-dose vaccine series compared to people who are
not immunocompromised.
This additional dose intended to improve immunocompromised people’s response to their initial vaccine
series.
Although CDC does not recommend additional doses or booster shots for any other population at this
time.CDC recommends that people with moderately to severely compromised immune systems receive
an additional dose of mRNA COVID-19 vaccine at least 28 days after a second dose of Pfizer-BioNTech
COVID-19 vaccine or Moderna COVID-19 vaccine.
Decreased Immune Response Among Immunocompromised People
People who are moderately to severely immunocompromised make up about 3% of the adult population
and are especially vulnerable to COVID-19 because they are more at risk of serious, prolonged illness.
Studies indicate some immunocompromised people don’t always build the same level of immunity after
vaccination the way non-immunocompromised people do, and may benefit from an additional dose to
ensure adequate protection against COVID-19. In small studies , fully vaccinated immunocompromised
people have accounted for a large proportion of hospitalized “breakthrough cases,” and that suggests
immunocompromised people are more likely to transmit the virus to household contacts.
Who Needs an Additional COVID-19 Vaccine?
Currently, CDC is recommending that moderately to severely immunocompromised people receive an
additional dose. This includes people who have:
Been receiving active cancer treatment for tumors or cancers of the blood
Received an organ transplant and are taking medicine to suppress the immune system
Received a stem cell transplant within the last 2 years or are taking medicine to suppress the immune
system
Moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)
Advanced or untreated HIV infection
Active treatment with high-dose corticosteroids or other drugs that may suppress your immune response
People should talk to their healthcare provider about their medical condition, and whether getting an
additional dose is appropriate for them.
Part B
Covid 19 Booster Shots for Moderately or Severely Immunocompromised People
People with moderately to severely compromised immune systems are especially susceptible to COVID-
19, and should not build an equivalent level of immunity to 2-dose vaccine series compared to people
that are not immunocompromised.
This additional dose intended to improve immunocompromised people’s response to their initial vaccine
series.
Although CDC doesn’t recommend additional doses or booster shots for the other population at this point
.CDC recommends that folks with moderately to severely compromised immune systems receive a
further dose of mRNA COVID-19 vaccine at least 28 days after a second dose of Pfizer-BioNTech
COVID-19 vaccine or Moderna COVID-19 vaccine.
Decreased Immune Response Among Immunocompromised People
People who are moderately to severely immunocompromised structure about 3% of the adult population
and are especially susceptible to COVID-19 because they’re more in danger of great , prolonged illness.
Studies indicate some immunocompromised people don’t always build an equivalent level of immunity
after vaccination the way non-immunocompromised people do, and should enjoy a further dose to make
sure adequate protection against COVID-19. In small studies , fully vaccinated immunocompromised
people have accounted for an outsized proportion of hospitalized “breakthrough cases,” which suggests
immunocompromised people are more likely to transmit the virus to household contacts.
Who Needs an Additional COVID-19 Vaccine?
Currently, CDC is recommending that moderately to severely immunocompromised people receive a
further dose. This includes people who have:
Been receiving active cancer treatment for tumors or cancers of the blood
Received an transplant and are taking medicine to suppress the system
Received a somatic cell transplant within the last 2 years or are taking medicine to suppress the system
Moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)
Advanced or untreated HIV infection
Active treatment with high-dose corticosteroids or other drugs which will suppress your immune reaction
People should ask their healthcare provider about their medical condition, and whether getting a further
dose is acceptable for them.
